Exogenous Antioxidants—Double‐Edged Swords in Cellular Redox State: Health Beneficial Effects at Physiologic Doses versus Deleterious Effects at High Doses

Bouayed, Jaouad; Bohn, Torsten

doi:10.4161/oxim.3.4.12858

Public

Exogenous Antioxidants—Double‐Edged Swords in Cellular Redox State: Health Beneficial Effects at Physiologic Doses versus Deleterious Effects at High Doses

Published in Oxidative Medicine and Cellular Longevity • Jan 1, 2010

Authors:

Jaouad Bouayed

Torsten Bohn

Abstract

The balance between oxidation and antioxidation is believed to be critical in maintaining healthy biological systems. Under physiological conditions, the human antioxidative defense system including e.g., superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione (GSH) and...

Subject

Antioxidant

Oxidative stress

Reactive oxygen species

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