Functional Relationship between Tumor-Associated Macrophages and Macrophage Colony-Stimulating Factor as Contributors to Cancer Progression

Laoui, Damya; Van Overmeire, Eva; De Baetselier, Patrick; A. Van Ginderachter, Jo; Raes, Geert

doi:10.3389/fimmu.2014.00489

Public

Functional Relationship between Tumor-Associated Macrophages and Macrophage Colony-Stimulating Factor as Contributors to Cancer Progression

Published in Frontiers in Immunology • Oct 7, 2014

Authors:

Damya Laoui

Eva Van Overmeire

Patrick De Baetselier

Abstract

The current review article describes the functional relationship between tumor-associated macrophages (TAM) as key cellular contributors to cancer malignancy on the one hand and macrophage-colony-stimulating factor (M-CSF or CSF-1) as an important molecular contributor on the other. We recapitulate ...

Subject

Macrophage colony-stimulating factor

Cancer research

Stromal cell

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