Common Risk Allele in Aromatic Antiepileptic-Drug Induced Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Han Chinese

Chung, Wen‐Hung; Chung, Wen‐Hung; Liu, Zhisheng; Chen, Chien-Hsiun; Hsih, Mo‐Song; Chung‐Yee Hui, Rosaline; Chu, Chia‐Yu; Chen, Yuan-Tsong

doi:10.2217/pgs.09.162

Public

Common Risk Allele in Aromatic Antiepileptic-Drug Induced Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Han Chinese

Published in Pharmacogenomics • Mar 1, 2010

Authors:

Wen‐Hung Chung

Zhisheng Liu

Abstract

AIMS: Compared with other categories of drugs, such as antibiotics and NSAIDs, antiepileptic therapies are associated with a high incidence of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). We previously reported that carbamazepine (CBZ)-SJS/TEN is strongly associated with the ...

Subject

Toxic epidermal necrolysis

Antiepileptic drug

Medicine

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