Folic acid for the prevention of colorectal adenomas: a randomized clinical trial.

Bernard F, Cole,; John A, Baron,; Robert S, Sandler,; Robert W, Haile,; Dennis J, Ahnen,; Robert S, Bresalier,; Gail, McKeown-Eyssen,; Robert W, Summers,; Richard I, Rothstein,; Carol A, Burke,; Dale C, Snover,; Timothy R, Church,; John I, Allen,; Douglas J, Robertson,; Gerald J, Beck,; John H, Bond,; Tim, Byers,; Jack S, Mandel,; Leila A, Mott,; Loretta H, Pearson,; Elizabeth L, Barry,; Judy R, Rees,; Norman, Marcon,; Fred, Saibil,; Per Magne, Ueland,; E Robert, Greenberg,

doi:10.1001/jama.297.21.2351

Public

Folic acid for the prevention of colorectal adenomas: a randomized clinical trial.

Published in JAMA • Jun 6, 2007

Authors:

Cole, Bernard F

Baron, John A

Sandler, Robert S

Abstract

CONTEXT: Laboratory and epidemiological data suggest that folic acid may have an antineoplastic effect in the large intestine. OBJECTIVE: To assess the safety and efficacy of folic acid supplementation for preventing colorectal adenomas. DESIGN, SETTING, AND PARTICIPANTS: A double-blind, placebo-con...

Subject

Adenoma

Adult

Aged

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