Advancing the Quorum in
            <i>Pseudomonas aeruginosa</i>
            : MvaT and the Regulation of
            <i>N</i>
            -Acylhomoserine Lactone Production and Virulence Gene Expression

P. Diggle, Stephen; Winzer, Klaus; Lazdunski, Andrée; Williams, Paul; Cámara, Miguel

doi:10.1128/jb.184.10.2576-2586.2002

Public

Advancing the Quorum in Pseudomonas aeruginosa : MvaT and the Regulation of N -Acylhomoserine Lactone Production and Virulence Gene Expression

Shared by NobleBlocks on May 15, 2002 • 12:00 AM UTC

Authors:

Stephen P. Diggle

Klaus Winzer

Andrée Lazdunski

Abstract

ABSTRACT Pseudomonas aeruginosa regulates the production of many exoproteins and secondary metabolites via a hierarchical quorum-sensing cascade through LasR and RhlR and their cognate signal molecules N- (3-oxododecanoyl)- l -homoserine lactone (3O-C12-HSL) and N- (butanoyl)- l -homoserine lactone ...

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