Continuous Lenalidomide Treatment for Newly Diagnosed Multiple Myeloma

Palumbo, Antonio; Hájek, Roman; Delforge, Michel; Kropff, Martin; Teresa Petrucci, Maria; Catalano, John; Gisslinger, Heinz; Wiktor-Jędrzejczak, W; Zodelava, Mamia; Weisel, Katja; Cascavilla, Nicola; Iosava, Genadi; Cavo, Michèle; Kłoczko, Janusz; Bladé, Joan; Beksaç, Meral; Špıčka, Ivan; Plesner, Torben; Radke, J.; Langer, Christian; Ben Yehuda, Dina; Corso, Alessandro; Herbein, Lindsay; Yu, Zhinuan; Mei, Jay; Jacques, Christian; Α. Dimopoulos, Meletios

doi:10.1056/nejmoa1112704

Public

Continuous Lenalidomide Treatment for Newly Diagnosed Multiple Myeloma

Published in New England Journal of Medicine • May 9, 2012

Authors:

Antonio Palumbo

Roman Hájek

Michel Delforge

Abstract

BACKGROUND: Lenalidomide has tumoricidal and immunomodulatory activity against multiple myeloma. This double-blind, multicenter, randomized study compared melphalan-prednisone-lenalidomide induction followed by lenalidomide maintenance (MPR-R) with melphalan-prednisone-lenalidomide (MPR) or melphala...

Subject

Lenalidomide

Multiple myeloma

Medicine

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