Preoperative Chemotherapy Plus Surgery Versus Surgery Plus Adjuvant Chemotherapy Versus Surgery Alone in Early-Stage Non–Small-Cell Lung Cancer

Felip, Enriqueta; Rosell, Rafael; Antonio Maestre, José; Manuel Rodríguez-Paniagua, José; Morán, Teresa; Astudillo, Julio; Alonso, Guillermo; Manuel Borro, José; Luis González-Larriba, José; Torres, Antonio; Camps, Carlos; Guijarro, Ricardo; Isla, Dolores; Aguiló, Rafael; Alberola, Vicente; Padilla, José; Sánchez-Palencia, Abel; Javier Sánchez, José; Hermosilla, Eduardo; Massuti, Bartomeu

doi:10.1200/jco.2009.27.6204

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Preoperative Chemotherapy Plus Surgery Versus Surgery Plus Adjuvant Chemotherapy Versus Surgery Alone in Early-Stage Non–Small-Cell Lung Cancer

Shared by NobleBlocks on Jul 1, 2010 • 12:00 AM UTC

Authors:

Enriqueta Felip

Rafael Rosell

José Antonio Maestre

Abstract

Purpose To address whether preoperative chemotherapy plus surgery or surgery plus adjuvant chemotherapy prolongs disease-free survival compared with surgery alone among patients with resectable non–small-cell lung cancer. Patients and Methods In this phase III trial, 624 patients with stage IA (tumo...

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