The virulence plasmid pWR100 and the repertoire of proteins secreted by the type III secretion apparatus of <i>Shigella flexneri</i>

Buchrieser, Carmen; Glaser, Philippe; Rusniok, Christophe; Nedjari, Hafed; d'Hauteville, H; Kunst, Frank; Sansonetti, Philippe; Parsot, Claude

doi:10.1046/j.1365-2958.2000.02179.x

Public

The virulence plasmid pWR100 and the repertoire of proteins secreted by the type III secretion apparatus of Shigella flexneri

Published in Molecular Microbiology • Nov 1, 2000

Authors:

Carmen Buchrieser

Philippe Glaser

Christophe Rusniok

Abstract

Bacteria of Shigella spp. are the causative agents of shigellosis. The virulence traits of these pathogens include their ability to enter into epithelial cells and induce apoptosis in macrophages. Expression of these functions requires the Mxi-Spa type III secretion apparatus and the secreted IpaA-D...

Subject

Shigella flexneri

Virulence

Biology

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