<i>Helicobacter pylori</i> SabA Adhesin in Persistent Infection and Chronic Inflammation

Mahdavi, Jafar; Sondén, Berit; Hurtig, Marina; O. Olfat, Farzad; Forsberg, Lina; Roche, Niamh; Ångström, Jonas; Larsson, Thomas; Teneberg, Susann; Karlsson, Karl‐Anders; Altraja, Siiri; Wadström, Torkel; Kersulyte, Dangeruta; E. Berg, Douglas; Dubois, A.; Petersson, Christoffer; Magnusson, Karl‐Eric; Norberg, Thomas; Lindh, Frank; Lundskog, Bertil; Arnqvist, Anna; Hammarström, Lennart; Borén, Thomas

doi:10.1126/science.1069076

Public

Helicobacter pylori SabA Adhesin in Persistent Infection and Chronic Inflammation

Published in Science • Jul 26, 2002

Authors:

Jafar Mahdavi

Berit Sondén

Marina Hurtig

Abstract

Helicobacter pylori adherence in the human gastric mucosa involves specific bacterial adhesins and cognate host receptors. Here, we identify sialyl-dimeric-Lewis x glycosphingolipid as a receptor for H. pylori and show that H. pylori infection induced formation of sialyl-Lewis x antigens in gastric ...

Subject

Bacterial adhesin

Helicobacter pylori

Glycoconjugate

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