The Vi conjugate typhoid vaccine is safe, elicits protective levels of IgG anti-Vi, and is compatible with routine infant vaccines.

VD, Thiem; FY, Lin; DG, Canh; NH, Son; DD, Anh; ND, Mao; C, Chu; SW, Hunt; JB, Robbins; R, Schneerson; SC, Szu

doi:10.1128/cvi.00532-10

Public

The Vi conjugate typhoid vaccine is safe, elicits protective levels of IgG anti-Vi, and is compatible with routine infant vaccines.

Shared by NobleBlocks on Mar 16, 2011 • 12:00 AM UTC

Authors:

Thiem VD

Lin FY

Canh DG

Abstract

Typhoid fever remains a serious problem in developing countries. Current vaccines are licensed for individuals who are 5 years old or older. A conjugate of the capsular polysaccharide (CP) of Salmonella enterica serovar Typhi (Vi) bound to recombinant exoprotein A of Pseudomonas aeruginosa (Vi-rEPA)...

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