Circulating microRNAs as stable blood-based markers for cancer detection

S. Mitchell, Patrick; K. Parkin, Rachael; M. Kroh, Evan; R. Fritz, Brian; K. Wyman, Stacia; L. Pogosova‐Agadjanyan, Era; C. Peterson, Amelia; Noteboom, Jennifer; O'Briant, Kathy; N. Allen, April; W. Lin, Daniel; Urban, Nicole; W. Drescher, Charles; S. Knudsen, Beatrice; L. Stirewalt, Derek; Gentleman, Robert; L. Vessella, Robert; S. Nelson, Peter; Martin, Daniel; Tewari, Muneesh

doi:10.1073/pnas.0804549105

Public

Circulating microRNAs as stable blood-based markers for cancer detection

Published in Proceedings of the National Academy of Sciences • Jul 28, 2008

Authors:

Patrick S. Mitchell

Rachael K. Parkin

Evan M. Kroh

Abstract

Improved approaches for the detection of common epithelial malignancies are urgently needed to reduce the worldwide morbidity and mortality caused by cancer. MicroRNAs (miRNAs) are small ( approximately 22 nt) regulatory RNAs that are frequently dysregulated in cancer and have shown promise as tissu...

Subject

Prostate cancer

microRNA

Cancer

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