Translocation of Inhaled Ultrafine Particles to the Brain

Oberdörster, Günter; D. Sharp, Z.; Atudorei, Viorel; Elder, Alison; Gelein, Robert; G. Kreyling, Wolfgang; Cox, Christopher

doi:10.1080/08958370490439597

Public

Translocation of Inhaled Ultrafine Particles to the Brain

Published in Inhalation Toxicology • Jan 1, 2004

Authors:

Günter Oberdörster

Z. D. Sharp

Viorel Atudorei

Abstract

Ultrafine particles (UFP, particles 50% of inhaled UFP can be depositing in the nasopharyngeal region during nasal breathing. Preliminary estimates from the present results show that approximately 20% of the UFP deposited on the olfactory mucosa of the rat can be translocated to the olfactory bulb. ...

Subject

Olfactory bulb

Ultrafine particle

Inhalation exposure

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