Use of the Humanized Anti-Epidermal Growth Factor Receptor Monoclonal Antibody h-R3 in Combination With Radiotherapy in the Treatment of Locally Advanced Head and Neck Cancer Patients

Crombet, Tania; Osorio, Marta; Cruz, Teresa; Gómez Roca, Carlos; del Castillo, Ramón; Mon, Rosa; Iznaga-Escobar, Normando; Figueredo, René; Koropatnick, James; Renginfo, Enrique; Fernández, Eduardo; Esteban Pineda Alvarez, Daniel; Torres, Olga; Ramos, Mayra; Leonard, I.; Pérez, Rolando; Lage, Agustín

doi:10.1200/jco.2004.03.089

Public

Use of the Humanized Anti-Epidermal Growth Factor Receptor Monoclonal Antibody h-R3 in Combination With Radiotherapy in the Treatment of Locally Advanced Head and Neck Cancer Patients

Published in Journal of Clinical Oncology • Apr 29, 2004

Authors:

Tania Crombet

Marta Osorio

Teresa Cruz

Abstract

PURPOSE: To evaluate safety and preliminary efficacy of the humanized anti-epidermal growth factor receptor monoclonal antibody h-R3 in combination with radiotherapy (RT) in unresectable head and neck cancer patients. Secondary end points were the measurement of h-R3 serum levels and the assessment ...

Subject

Medicine

Head and neck cancer

Antibody

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