X-ray structure of the FimC-FimH chaperone-adhesin complex from uropathogenic Escherichia coli.

D, Choudhury; A, Thompson; V, Stojanoff; S, Langermann; J, Pinkner; SJ, Hultgren; SD, Knight

doi:10.1126/science.285.5430.1061

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X-ray structure of the FimC-FimH chaperone-adhesin complex from uropathogenic Escherichia coli.

Shared by NobleBlocks on Aug 1, 1999 • 12:00 AM UTC

Authors:

Choudhury D

Thompson A

Stojanoff V

Abstract

Type 1 pili-adhesive fibers expressed in most members of the Enterobacteriaceae family-mediate binding to mannose receptors on host cells through the FimH adhesin. Pilus biogenesis proceeds by way of the chaperone/usher pathway. The x-ray structure of the FimC-FimH chaperone-adhesin complex from uro...

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