Synthetic malaria peptide vaccine elicits high levels of antibodies in vaccinees of defined HLA genotypes.

EH, Nardin; GA, Oliveira; JM, Calvo-Calle; ZR, Castro; RS, Nussenzweig; B, Schmeckpeper; BF, Hall; C, Diggs; S, Bodison; R, Edelman

doi:10.1086/315871

Public

Synthetic malaria peptide vaccine elicits high levels of antibodies in vaccinees of defined HLA genotypes.

Shared by NobleBlocks on Oct 9, 2000 • 12:00 AM UTC

Authors:

Nardin EH

Oliveira GA

Calvo-Calle JM

Abstract

A multiple antigen peptide (MAP) malaria vaccine containing minimal Plasmodium falciparum circumsporozoite protein repeat epitopes was assessed for safety and immunogenicity in volunteers of known class II genotypes. The MAP/alum/QS-21 vaccine formulation elicited high levels of parasite-specific an...

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