Cetuximab for the Treatment of Colorectal Cancer

J. Jonker, Derek; J. O’Callaghan, Chris; S. Karapetis, Christos; Zalcberg, John; Tu, Dongsheng; Au, Heather-Jane; Berry, Scott; Krahn, Marianne; Price, Timothy; J. Simes, R.; C. Tebbutt, Niall; van Hazel, Guy; Wierzbicki, Rafal; Langer, Christiane; J. Moore, Malcolm

doi:10.1056/nejmoa071834

Public

Cetuximab for the Treatment of Colorectal Cancer

Published in New England Journal of Medicine • Nov 14, 2007

Authors:

Derek J. Jonker

Chris J. O’Callaghan

Christos S. Karapetis

Abstract

BACKGROUND: Cetuximab, an IgG1 chimeric monoclonal antibody against epidermal growth factor receptor (EGFR), has activity against colorectal cancers that express EGFR. METHODS: From December 2003 to August 2005, 572 patients who had colorectal cancer expressing immunohistochemically detectable EGFR ...

Subject

Cetuximab

Medicine

Irinotecan

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