Comparison of the FDA-Approved CDC DENV-1-4 Real-Time Reverse Transcription-PCR with a Laboratory-Developed Assay for Dengue Virus Detection and Serotyping

J. Waggoner, Jesse; Abeynayake, Janaki; K. Sahoo, Malaya; Gresh, Lionel; Téllez, Yolanda; González, Karla; Ballesteros, Gabriela; P. Guo, Frances; Balmaseda, Ángel; Karunaratne, Kumudu; Harris, Eva; A. Pinsky, Benjamin

doi:10.1128/jcm.01359-13

Public

Comparison of the FDA-Approved CDC DENV-1-4 Real-Time Reverse Transcription-PCR with a Laboratory-Developed Assay for Dengue Virus Detection and Serotyping

Published in Journal of Clinical Microbiology • Aug 1, 2013

Authors:

Jesse J. Waggoner

Janaki Abeynayake

Malaya K. Sahoo

Abstract

Dengue virus (DENV) is the agent of the most common vector-borne disease worldwide. Using 199 clinical samples collected from Nicaragua and Sri Lanka, a laboratory-developed DENV multiplex real-time reverse transcription-PCR (rRT-PCR) proved more clinically sensitive than the FDA-approved CDC assay ...

Subject

Dengue virus

Virology

Serotype

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