Long‐term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma

S. Rosen, Lee; Gordon, David; Kaminski, Mary; Howell, Anthony; Belch, Andrew; Mackey, John; Apffelstaedt, Justus; A. Hussein, Mohamad; E. Coleman, Robert; J. Reitsma, Dirk; Chen, Bee‐Lian; J. Seaman, John

doi:10.1002/cncr.11701

Public

Long‐term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma

Shared by NobleBlocks on Aug 28, 2003 • 12:00 AM UTC

Authors:

Lee S. Rosen

David Gordon

Mary Kaminski

Abstract

Abstract BACKGROUND The goal of the current study was to compare the long‐term (25‐month) safety and efficacy of zoledronic acid with pamidronate in patients with bone lesions secondary to advanced breast carcinoma or multiple myeloma. METHODS Patients ( n = 1648) were randomized to receive 4 mg or ...

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