Long‐term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma

S. Rosen, Lee; Gordon, David; Kaminski, Mary; Howell, Anthony; R. Belch, Andrew; R. Mackey, John; Apffelstaedt, Justus; A. Hussein, Mohamad; E. Coleman, Robert; J. Reitsma, Dirk; Chen, Bee‐Lian; J. Seaman, John

doi:10.1002/cncr.11701

Public

Long‐term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma

Published in Cancer • Aug 29, 2003

Authors:

Lee S. Rosen

David Gordon

Mary Kaminski

Abstract

BACKGROUND: The goal of the current study was to compare the long-term (25-month) safety and efficacy of zoledronic acid with pamidronate in patients with bone lesions secondary to advanced breast carcinoma or multiple myeloma. METHODS: Patients (n = 1648) were randomized to receive 4 mg or 8 mg (re...

Subject

Zoledronic acid

Medicine

Bisphosphonate

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