Cutting Edge: Repurification of Lipopolysaccharide Eliminates Signaling Through Both Human and Murine Toll-Like Receptor 2

Hirschfeld, Matthew; Ma, Ying; H. Weis, John; N. Vogel, Stefanie; J. Weis, Janis

doi:10.4049/jimmunol.165.2.618

Public

Cutting Edge: Repurification of Lipopolysaccharide Eliminates Signaling Through Both Human and Murine Toll-Like Receptor 2

Published in The Journal of Immunology • Jul 1, 2000

Authors:

Matthew Hirschfeld

Ying Ma

John H. Weis

Abstract

Toll-like receptor (TLR) 2 has recently been associated with cellular responses to numerous microbial products, including LPS and bacterial lipoproteins. However, many preparations of LPS contain low concentrations of highly bioactive contaminants described previously as "endotoxin protein," suggest...

Subject

Lipopolysaccharide

TLR2

TLR4

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