Genome sequence-based species delimitation with confidence intervals and improved distance functions

P. Meier‐Kolthoff, Jan; F. Auch, Alexander; Klenk, Hans-Peter; Göker, Markus

doi:10.1186/1471-2105-14-60

Public

Genome sequence-based species delimitation with confidence intervals and improved distance functions

Published in BMC Bioinformatics • Feb 21, 2013

Authors:

Jan P. Meier‐Kolthoff

Alexander F. Auch

Hans-Peter Klenk

Abstract

BACKGROUND: For the last 25 years species delimitation in prokaryotes (Archaea and Bacteria) was to a large extent based on DNA-DNA hybridization (DDH), a tedious lab procedure designed in the early 1970s that served its purpose astonishingly well in the absence of deciphered genome sequences. With ...

Subject

Genome

Biology

Resampling

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