Differential regulation of transforming growth factor beta and interleukin 2 genes in human T cells: demonstration by usage of novel competitor DNA constructs in the quantitative polymerase chain reaction.

Li, Bo; K. Sehajpal, P.; Khanna, Ashwani; Vlassara, Helen; Cerami, Anthony; H Stenzel, K; Suthanthiran, Manikkam

doi:10.1084/jem.174.5.1259

Public

Differential regulation of transforming growth factor beta and interleukin 2 genes in human T cells: demonstration by usage of novel competitor DNA constructs in the quantitative polymerase chain reaction.

Published in The Journal of Experimental Medicine • Nov 1, 1991

Authors:

Bo Li

P. K. Sehajpal

Ashwani Khanna

Abstract

The regulation of mRNA encoding transforming growth factor beta (TGF-beta) and interleukin 2 (IL-2) in normal human T cells was explored using novel competitor DNA constructs in the quantitative polymerase chain reaction and accessory cell-independent T cell activation models. Our experimental desig...

Subject

Biology

Transforming growth factor beta

Ionomycin

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