Breakdown in cortical effective connectivity during midazolam-induced loss of consciousness

Ferrarelli, Fabio; Massimini, Marcello; Sarasso, Simone; G. Casali, Adenauer; A. Riedner, Brady; Angelini, Giuditta; Tononi, Giulio; A. Pearce, Robert

doi:10.1073/pnas.0913008107

Public

Breakdown in cortical effective connectivity during midazolam-induced loss of consciousness

Published in Proceedings of the National Academy of Sciences • Jan 25, 2010

Authors:

Fabio Ferrarelli

Marcello Massimini

Simone Sarasso

Abstract

By employing transcranial magnetic stimulation (TMS) in combination with high-density electroencephalography (EEG), we recently reported that cortical effective connectivity is disrupted during early non-rapid eye movement (NREM) sleep. This is a time when subjects, if awakened, may report little or...

Subject

Wakefulness

Non-rapid eye movement sleep

Electroencephalography

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