Microbiota of De-Novo Pediatric IBD: Increased Faecalibacterium Prausnitzii and Reduced Bacterial Diversity in Crohn's But Not in Ulcerative Colitis

Hansen, Richard; K. Russell, Richard; Reiff, Caroline; Louis, Petra; M. McIntosh, Freda; H. Berry, Susan; Mukhopadhya, Indrani; W. Bisset, Michael; R. Barclay, A.; Bishop, J.; M. Flynn, Diana; McGrogan, Paraic; Loganathan, Sabarinathan; Mahdi, Gamal; J. Flint, Harry; El‐Omar, Emad; L. Hold, Georgina

doi:10.1038/ajg.2012.335

Public

Microbiota of De-Novo Pediatric IBD: Increased Faecalibacterium Prausnitzii and Reduced Bacterial Diversity in Crohn's But Not in Ulcerative Colitis

Published in The American Journal of Gastroenterology • Oct 9, 2012

Authors:

Richard Hansen

Richard K. Russell

Caroline Reiff

Abstract

OBJECTIVES: The gastrointestinal microbiota is considered important in inflammatory bowel disease (IBD) pathogenesis. Discoveries from established disease cohorts report reduced bacterial diversity, changes in bacterial composition, and a protective role for Faecalibacterium prausnitzii in Crohn's d...

Subject

Ulcerative colitis

Pyrosequencing

Inflammatory bowel disease

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