Microbiota of de-novo pediatric IBD: increased Faecalibacterium prausnitzii and reduced bacterial diversity in Crohn's but not in ulcerative colitis.

Hansen, Richard; K Russell, Richard; Reiff, Caroline; Louis, Petra; McIntosh, Freda; H Berry, Susan; Mukhopadhya, Indrani; Michael Bisset, W; R Barclay, Andy; Bishop, Jon; M Flynn, Diana; McGrogan, Paraic; Loganathan, Sabarinathan; Mahdi, Gamal; J Flint, Harry; M El-Omar, Emad; L Hold, Georgina

doi:10.1038/ajg.2012.335

Public

Microbiota of de-novo pediatric IBD: increased Faecalibacterium prausnitzii and reduced bacterial diversity in Crohn's but not in ulcerative colitis.

Shared by NobleBlocks on Dec 1, 2012 • 12:00 AM UTC

Authors:

Richard Hansen

Richard K Russell

Caroline Reiff

Abstract

OBJECTIVES: The gastrointestinal microbiota is considered important in inflammatory bowel disease (IBD) pathogenesis. Discoveries from established disease cohorts report reduced bacterial diversity, changes in bacterial composition, and a protective role for Faecalibacterium prausnitzii in Crohn's d...

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