CCK-8 and CCK-58 differ in their effects on nocturnal solid meal pattern in undisturbed rats

Goebel‐Stengel, Miriam; Stengel, Andreas; Wang, Lixin; Ohning, Gordon; Taché, Yvette; R. Reeve, Joseph

doi:10.1152/ajpregu.00365.2011

Public

CCK-8 and CCK-58 differ in their effects on nocturnal solid meal pattern in undisturbed rats

Published in American Journal of Physiology-Regulatory, Integrative and Comparative Physiology • Aug 9, 2012

Authors:

Miriam Goebel‐Stengel

Andreas Stengel

Lixin Wang

Abstract

Various molecular forms of CCK reduce food intake in rats. Although CCK-8 is the most studied form, we reported that CCK-58 is the only detectable endocrine peptide form in rats. We investigated the dark-phase rat chow intake pattern following injection of CCK-8 and CCK-58. Ad libitum-fed male Sprag...

Subject

Cholecystokinin

Internal medicine

Endocrinology

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