MYC protein expression and genetic alterations have prognostic impact in patients with diffuse large B-cell lymphoma treated with immunochemotherapy.

Valera, Alexandra; López-Guillermo, Armando; Cardesa-Salzmann, Teresa; Climent, Fina; González-Barca, Eva; Mercadal, Santiago; Espinosa, Iñigo; Novelli, Silvana; Briones, Javier; L Mate, José; Salamero, Olga; M Sancho, Juan; Arenillas, Leonor; Serrano, Sergi; Erill, Nadina; Martínez, Daniel; Castillo, Paola; Rovira, Jordina; Martínez, Antonio; Campo, Elias; Colomo, Luis; per l’Estudi dels Limfomes de Catalunya i Balears (GELCAB), Grup

doi:10.3324/haematol.2013.086173

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MYC protein expression and genetic alterations have prognostic impact in patients with diffuse large B-cell lymphoma treated with immunochemotherapy.

Shared by NobleBlocks on Oct 1, 2013 • 12:00 AM UTC

Authors:

Alexandra Valera

Armando López-Guillermo

Teresa Cardesa-Salzmann

Abstract

MYC alterations influence the survival of patients with diffuse large B-cell lymphoma. Most studies have focused on MYC translocations but there is little information regarding the impact of numerical alterations and protein expression. We analyzed the genetic alterations and protein expression of M...

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