Central nervous system viral invasion and inflammation during acute HIV infection.

Valcour, Victor; Chalermchai, Thep; Sailasuta, Napapon; Marovich, Mary; Lerdlum, Sukalaya; Suttichom, Duanghathai; C Suwanwela, Nijasri; Jagodzinski, Linda; Michael, Nelson; Spudich, Serena; van Griensven, Frits; de Souza, Mark; Kim, Jerome; Ananworanich, Jintanat; 010 Study Group, RV254/SEARCH

doi:10.1093/infdis/jis326

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Central nervous system viral invasion and inflammation during acute HIV infection.

Shared by NobleBlocks on Jul 15, 2012 • 12:00 AM UTC

Authors:

Victor Valcour

Thep Chalermchai

Napapon Sailasuta

Abstract

BACKGROUND: Understanding the earliest central nervous system (CNS) events during human immunodeficiency virus (HIV) infection is crucial to knowledge of neuropathogenesis, but these have not previously been described in humans. METHODS: Twenty individuals who had acute HIV infection (Fiebig stages ...

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