Levofloxacin to Prevent Bacterial Infection in Patients with Cancer and Neutropenia

Bucaneve, Giampaolo; Micozzi, Alessandra; Menichetti, Francesco; Martino, Pietro; Dionisi, Marco; Martinelli, Giovanni; Allione, Bernardino; D’Antonio, Domenico; Buelli, Maurizio; Nosari, Annamaria; Cilloni, Daniela; Zuffa, Eliana; Cantaffa, Renato; Specchia, Giorgina; Amadori, Sergio; Fabbiano, Francesco; Lambertenghi Deliliers, Giorgio; Lauria, Francesco; Foà, Robin; Del Favero, A.

doi:10.1056/nejmoa044097

Public

Levofloxacin to Prevent Bacterial Infection in Patients with Cancer and Neutropenia

Published in New England Journal of Medicine • Sep 7, 2005

Authors:

Giampaolo Bucaneve

Alessandra Micozzi

Francesco Menichetti

Abstract

BACKGROUND: The prophylactic use of fluoroquinolones in patients with cancer and neutropenia is controversial and is not a recommended intervention. METHODS: We randomly assigned 760 consecutive adult patients with cancer in whom chemotherapy-induced neutropenia (<1000 neutrophils per cubic millimet...

Subject

Medicine

Levofloxacin

Neutropenia

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