Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation

Kääb, Stefan; Darbar, Dawood; van Noord, Charlotte; Dupuis, Josée; Pfeufer, Arne; Newton-Cheh, Chris; B. Schnabel, Renate; Makino, S; F. Sinner, Moritz; J. Kannankeril, Prince; Maria Beckmann, Britt; Choudry, Subbarao; S. Donahue, Brian; Heeringa, Jan; Perz, Siegfried; L. Lunetta, Kathryn; G. Larson, Martin; Levy, Daniel; A. MacRae, Calum; N. Ruskin, Jeremy; Wacker, A.; Schömig, Albert; Wichmann, H.‐Erich; Steinbeck, Gerhard; Meitinger, Thomas; G. Uitterlinden, André; C.M. Witteman, Jacqueline; M Roden, D; J. Benjamin, Emelia; T. Ellinor, Patrick

doi:10.1093/eurheartj/ehn578

Public

Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation

Published in European Heart Journal • Dec 9, 2008

Authors:

Stefan Kääb

Dawood Darbar

Charlotte van Noord

Abstract

AIMS: A recent genome-wide association study identified a haplotype block on chromosome 4q25 associated with atrial fibrillation (AF). We sought to replicate this association in four independent cohorts. METHODS AND RESULTS: The Framingham Heart Study and Rotterdam Study are community-based longitud...

Subject

Medicine

Rotterdam Study

Odds ratio

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