First-Trimester or Second-Trimester Screening, or Both, for Down's Syndrome

D. Malone, Fergal; A. Canick, Jacob; H. Ball, Robert; A. Nyberg, David; H. Comstock, Christine; Bukowski, Radek; L. Berkowitz, Richard; J. Gross, Susan; Dugoff, Lorraine; Craigo, Sabrina; E. Timor‐Tritsch, Ilan; R. Carr, Stephen; M. Wolfe, Honor; A. Dukes, Kimberly; W. Bianchi, Diana; R. Rudnicka, Alicja; Hackshaw, Allan; Lambert‐Messerlian, Geralyn; Wald, Nicholas; E. D’Alton, Mary

doi:10.1056/nejmoa043693

Public

First-Trimester or Second-Trimester Screening, or Both, for Down's Syndrome

Published in New England Journal of Medicine • Nov 9, 2005

Authors:

Fergal D. Malone

Jacob A. Canick

Robert H. Ball

Abstract

BACKGROUND: It is uncertain how best to screen pregnant women for the presence of fetal Down's syndrome: to perform first-trimester screening, to perform second-trimester screening, or to use strategies incorporating measurements in both trimesters. METHODS: Women with singleton pregnancies underwen...

Subject

Medicine

Gestation

Obstetrics

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