First-trimester or second-trimester screening, or both, for Down's syndrome.

FD, Malone; JA, Canick; RH, Ball; DA, Nyberg; CH, Comstock; R, Bukowski; RL, Berkowitz; SJ, Gross; L, Dugoff; SD, Craigo; IE, Timor-Tritsch; SR, Carr; HM, Wolfe; K, Dukes; DW, Bianchi; AR, Rudnicka; AK, Hackshaw; G, Lambert-Messerlian; NJ, Wald; ME, D'Alton

doi:10.1056/nejmoa043693

Public

First-trimester or second-trimester screening, or both, for Down's syndrome.

Shared by NobleBlocks on Nov 1, 2005 • 12:00 AM UTC

Authors:

Malone FD

Canick JA

Ball RH

Abstract

Background It is uncertain how best to screen pregnant women for the presence of fetal Down's syndrome: to perform first-trimester screening, to perform second-trimester screening, or to use strategies incorporating measurements in both trimesters.Methods Women with singleton pregnancies underwent f...

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