Avian Influenza (H5N1) Viruses Isolated from Humans in Asia in 2004 Exhibit Increased Virulence in Mammals

R. Maines, Taronna; Hua Lu, Xui; M. Erb, Steven; E. Edwards, Lindsay; Guarner, Jeannette; W. Greer, Patricia; C. Nguyen, Doan; J. Szretter, Kristy; Chen, Li‐Mei; Thawatsupha, Pranee; Chittaganpitch, Malinee; Waicharoen, Sunthareeya; Thi Ngoc Nguyen, Diep; Nguyen, Tung; H. T. Nguyen, Hanh; Kim, Jaehong; T. Hoang, Long; Kang, Chun; S. Phuong, Lien; Lim, Wilina; R. Zaki, Sherif; O. Donis, Rubén; J. Cox, Nancy; M. Katz, Jacqueline; M. Tumpey, Terrence

doi:10.1128/jvi.79.18.11788-11800.2005

Public

Avian Influenza (H5N1) Viruses Isolated from Humans in Asia in 2004 Exhibit Increased Virulence in Mammals

Published in Journal of Virology • Sep 1, 2005

Authors:

Taronna R. Maines

Xui Hua Lu

Steven M. Erb

Abstract

The spread of highly pathogenic avian influenza H5N1 viruses across Asia in 2003 and 2004 devastated domestic poultry populations and resulted in the largest and most lethal H5N1 virus outbreak in humans to date. To better understand the potential of H5N1 viruses isolated during this epizootic event...

Subject

Virulence

Biology

Influenza A virus subtype H5N1

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