Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia

P Hellyer, Thomas; Conway Morris, Andrew; F. McAuley, Daniel; Walsh, Timothy; Anderson, Niall; Singh, Suveer; Dark, Paul; Roy, Alistair; Baudouin, Simon; E. Wright, Stephen; D. Perkins, Gavin; Kefala, Kallirroi; Jeffels, Melinda; McMullan, Ronan; O’Kane, Cecilia; Spencer, Craig; Laha, Shondipon; Robin, Nicole; Gossain, Savita; Gould, Kate; Ruchaud‐Sparagano, Marie‐Hélène; Scott, Jonathan; Browne, Emma; Macfarlane, James; Wiscombe, Sarah; Widdrington, John; Dimmick, Ian; F. Laurenson, Ian; Nauwelaers, Frans; John Simpson, A.

doi:10.1136/thoraxjnl-2014-205766

Public

Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia

Published in Thorax • Oct 8, 2014

Authors:

Thomas P Hellyer

Andrew Conway Morris

Daniel F. McAuley

Abstract

BACKGROUND: Excessive use of empirical antibiotics is common in critically ill patients. Rapid biomarker-based exclusion of infection may improve antibiotic stewardship in ventilator-acquired pneumonia (VAP). However, successful validation of the usefulness of potential markers in this setting is ex...

Subject

Medicine

Bronchoalveolar lavage

Ventilator-associated pneumonia

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