Acute Skeletal Muscle Wasting in Critical Illness

Puthucheary, Zudin; Rawal, Jaikitry; McPhail, Mark; Connolly, Bronwen; Ratnayake, Gamunu; Chan, Pearl; S Hopkinson, Nicholas; Padhke, Rahul; Dew, Tracy; S. Sidhu, Paul; P. Velloso, Cristiana; Seymour, John; C. Agley, Chibeza; Selby, Anna; C. Limb, Marie; M. Edwards, Lindsay; Smith, Kenneth; Rowlerson, A; J. Rennie, Michael; Moxham, John; D. R. Harridge, Stephen; Hart, Nicholas; Montgomery, Hugh

doi:10.1001/jama.2013.278481

Public

Acute Skeletal Muscle Wasting in Critical Illness

Published in JAMA • Oct 9, 2013

Authors:

Zudin Puthucheary

Jaikitry Rawal

Mark McPhail

Abstract

IMPORTANCE: Survivors of critical illness demonstrate skeletal muscle wasting with associated functional impairment. OBJECTIVE: To perform a comprehensive prospective characterization of skeletal muscle wasting, defining the pathogenic roles of altered protein synthesis and breakdown. DESIGN, SETTIN...

Subject

Medicine

Wasting

Skeletal muscle

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