A hierarchical quorum‐sensing cascade in Pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationary‐phase sigma factor RpoS

Latifi, A.; Foglino, M.; Tanaka, K.; Williams, P.; Lazdunski, A.

doi:10.1046/j.1365-2958.1996.00063.x

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A hierarchical quorum‐sensing cascade in Pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationary‐phase sigma factor RpoS

Shared by NobleBlocks on Sep 1, 1996 • 12:00 AM UTC

Authors:

A. Latifi

M. Foglino

K. Tanaka

Abstract

Summary In Pseudomonas aeruginosa , the production of many virulence factors and secondary metabolites is regulated in concert with cell density through quorum sensing. Two quorum‐sensing regulons have been identified in which the LuxR homologues LasR and RhIR are activated by N ‐(3‐oxododecanoyl)‐ ...

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