Cancer Cachexia in the Age of Obesity: Skeletal Muscle Depletion Is a Powerful Prognostic Factor, Independent of Body Mass Index

Martin, Lisa; Birdsell, Laura; Macdonald, Neil; Reiman, Tony; Thomas Clandinin, M.; J. McCargar, Linda; A. Murphy, Rachel; Ghosh, Sunita; B. Sawyer, Michael; E. Baracos, Vickie

doi:10.1200/jco.2012.45.2722

Public

Cancer Cachexia in the Age of Obesity: Skeletal Muscle Depletion Is a Powerful Prognostic Factor, Independent of Body Mass Index

Published in Journal of Clinical Oncology • Mar 26, 2013

Authors:

Lisa Martin

Laura Birdsell

Neil Macdonald

Abstract

PURPOSE: Emerging evidence suggests muscle depletion predicts survival of patients with cancer. PATIENTS AND METHODS: At a cancer center in Alberta, Canada, consecutive patients with cancer (lung or GI; N = 1,473) were assessed at presentation for weight loss history, lumbar skeletal muscle index, a...

Subject

Medicine

Underweight

Body mass index

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