Estimating Glomerular Filtration Rate from Serum Creatinine and Cystatin C

A. Inker, Lesley; H. Schmid, Christopher; Tighiouart, Hocine; H. Eckfeldt, John; I. Feldman, Harold; Greene, Tom; W. Kusek, John; Manzi, Jane; Van Lente, Frederick; Lucy Zhang, Yaping; Coresh, Josef; S. Levey, Andrew

doi:10.1056/nejmoa1114248

Public

Estimating Glomerular Filtration Rate from Serum Creatinine and Cystatin C

Published in New England Journal of Medicine • Jul 5, 2012

Authors:

Lesley A. Inker

Christopher H. Schmid

Hocine Tighiouart

Abstract

BACKGROUND: Estimates of glomerular filtration rate (GFR) that are based on serum creatinine are routinely used; however, they are imprecise, potentially leading to the overdiagnosis of chronic kidney disease. Cystatin C is an alternative filtration marker for estimating GFR. METHODS: Using cross-se...

Subject

Renal function

Cystatin C

Medicine

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