Large-scale expression study of human mesial temporal lobe epilepsy: evidence for dysregulation of the neurotransmission and complement systems in the entorhinal cortex

Jamali, Sarah; Bartoloméi, Fabrice; Robaglia‐Schlupp, Andrée; Massacrier, Annick; Peragut, J.C.; Régis, Jean; Dufour, H.; Ravid, Rivka; Roll, Patrice; Pereira, Sandrine; Royer, Barbara; Roeckel-Trévisiol, Nathalie; Fontaine, Marc; Guye, Maxime; Boucraut, José; Chauvel, Patrick; Cau, Pierre; Szepetowski, Pierre

doi:10.1093/brain/awl001

Public

Large-scale expression study of human mesial temporal lobe epilepsy: evidence for dysregulation of the neurotransmission and complement systems in the entorhinal cortex

Published in Brain • Jan 6, 2006

Authors:

Sarah Jamali

Fabrice Bartoloméi

Andrée Robaglia‐Schlupp

Abstract

Human mesial temporal lobe epilepsies (MTLE) are the most frequent form of partial epilepsies and display frequent pharmacoresistance. The molecular alterations underlying human MTLE remain poorly understood. A two-step transcriptional analysis consisting in cDNA microarray experiments followed by q...

Subject

Biology

Entorhinal cortex

Neocortex

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