Brain Swelling and Death in Children with Cerebral Malaria

B. Seydel, Karl; Kampondeni, Samuel; Valim, Clarissa; J. Potchen, Michael; A. Milner, Danny; Muwalo, Francis; L. Birbeck, Gretchen; G. Bradley, William; Fox, Lindsay; J. Glover, Simon; Hammond, Colleen; S. Heyderman, Robert; Chilingulo, Cowles; E. Molyneux, Malcolm; E. Taylor, Terrie

doi:10.1056/nejmoa1400116

Public

Brain Swelling and Death in Children with Cerebral Malaria

Published in New England Journal of Medicine • Mar 18, 2015

Authors:

Karl B. Seydel

Samuel Kampondeni

Clarissa Valim

Abstract

BACKGROUND: Case fatality rates among African children with cerebral malaria remain in the range of 15 to 25%. The key pathogenetic processes and causes of death are unknown, but a combination of clinical observations and pathological findings suggests that increased brain volume leading to raised i...

Subject

Cerebral Malaria

Medicine

Intracranial pressure

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