Risk of upper gastrointestinal ulcer bleeding associated with selective cyclo-oxygenase-2 inhibitors, traditional non-aspirin non-steroidal anti-inflammatory drugs, aspirin and combinations

Lanas, Ángel; A. Garcı́a Rodrı́guez, Luis; Arroyo, M; Gomollón, Fernando; Feu, Faust; González‐Pérez, Antonio; Zapata, E.; Bastida, Guillermo; Rodrigo, Luı́s; Santolaria, Santos; Güell, Maria-Rosa; Martín de Argila, Carlos; Quintero, Enrique; Borda, Fernando; Piqué, J.M.

doi:10.1136/gut.2005.080754

Public

Risk of upper gastrointestinal ulcer bleeding associated with selective cyclo-oxygenase-2 inhibitors, traditional non-aspirin non-steroidal anti-inflammatory drugs, aspirin and combinations

Published in Gut • May 10, 2006

Authors:

Ángel Lanas

Luis A. Garcı́a Rodrı́guez

M Arroyo

Abstract

BACKGROUND: The risks and benefits of coxibs, non-steroidal anti-inflammatory drugs (NSAIDs), and aspirin treatment are under intense debate. OBJECTIVE: To determine the risk of peptic ulcer upper gastrointestinal bleeding (UGIB) associated with the use of coxibs, traditional NSAIDs, aspirin or comb...

Subject

Medicine

Aspirin

Rofecoxib

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