Genomic regulatory blocks encompass multiple neighboring genes and maintain conserved synteny in vertebrates.

H, Kikuta; M, Laplante; P, Navratilova; AZ, Komisarczuk; PG, Engström; D, Fredman; A, Akalin; M, Caccamo; I, Sealy; K, Howe; J, Ghislain; G, Pezeron; P, Mourrain; S, Ellingsen; AC, Oates; C, Thisse; B, Thisse; I, Foucher; B, Adolf; A, Geling; B, Lenhard; TS, Becker

doi:10.1101/gr.6086307

Public

Genomic regulatory blocks encompass multiple neighboring genes and maintain conserved synteny in vertebrates.

Shared by NobleBlocks on Mar 26, 2007 • 12:00 AM UTC

Authors:

Kikuta H

Laplante M

Navratilova P

Abstract

We report evidence for a mechanism for the maintenance of long-range conserved synteny across vertebrate genomes. We found the largest mammal-teleost conserved chromosomal segments to be spanned by highly conserved noncoding elements (HCNEs), their developmental regulatory target genes, and phylogen...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!