Tiotropium in Asthma Poorly Controlled with Standard Combination Therapy

A.M. Kerstjens, Huib; Engel, Michael; Dahl, Ronald; Paggiaro, Pierluigi; Beck, Ekkehard; Vandewalker, Mark; Sigmund, Ralf; Seibold, Wolfgang; Moroni-Zentgraf, Petra; D. Bateman, Eric

doi:10.1056/nejmoa1208606

Public

Tiotropium in Asthma Poorly Controlled with Standard Combination Therapy

Published in New England Journal of Medicine • Sep 2, 2012

Authors:

Huib A.M. Kerstjens

Michael Engel

Ronald Dahl

Abstract

BACKGROUND: Some patients with asthma have frequent exacerbations and persistent airflow obstruction despite treatment with inhaled glucocorticoids and long-acting beta-agonists (LABAs). METHODS: In two replicate, randomized, controlled trials involving 912 patients with asthma who were receiving in...

Subject

Medicine

Asthma

Bronchodilator Agents

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