The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

McKenna, Aaron; G. Hanna, Matthew; Banks, Eric; Sivachenko, Andrey; Cibulskis, Kristian; Kernytsky, Andrew; Garimella, Kiran; Altshuler, David; Gabriel, Stacey; J. Daly, Mark; A. DePristo, Mark

doi:10.1101/gr.107524.110

Public

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

Published in Genome Research • Jul 19, 2010

Authors:

Aaron McKenna

Matthew G. Hanna

Eric Banks

Abstract

Next-generation DNA sequencing (NGS) projects, such as the 1000 Genomes Project, are already revolutionizing our understanding of genetic variation among individuals. However, the massive data sets generated by NGS--the 1000 Genome pilot alone includes nearly five terabases--make writing feature-ric...

Subject

Computer science

Genome

Correctness

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