Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions

J Levi, A; M. Arias, I.

doi:10.1172/jci106182

Public

Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions

Published in Journal of Clinical Investigation • Nov 1, 1969

Authors:

A J Levi

I. M. Arias

Abstract

Two hepatic cytoplasmic protein fractions, designated Y and Z, which bind sulfobromophthalein (BSP), bilirubin, and other organic anions, have been separated by G75 Sephadex gel filtration. The physiologic role of these protein fractions has been investigated. They are present in the 110,000 g super...

Subject

Sulfobromophthalein

Bilirubin

Sephadex

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