Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins

Subra, Caroline; Grand, David; Laulagnier, Karine; Stella, Alexandre; Lambeau, Gérard; R. Paillasse, Michaël; de Médina, Philippe; Monsarrat, Bernard; Perret, Bertrand; Silvente‐Poirot, Sandrine; Poirot, Marc; Record, Michel

doi:10.1194/jlr.m003657

Public

Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins

Published in Journal of Lipid Research • Apr 28, 2010

Authors:

Caroline Subra

David Grand

Karine Laulagnier

Abstract

Exosomes are bioactive vesicles released from multivesicular bodies (MVB) by intact cells and participate in intercellular signaling. We investigated the presence of lipid-related proteins and bioactive lipids in RBL-2H3 exosomes. Besides a phospholipid scramblase and a fatty acid binding protein, t...

Subject

Transcellular

Microvesicles

Vesicle

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