Emergence of Carbapenem-Resistant Klebsiella Species Possessing the Class A Carbapenem-Hydrolyzing KPC-2 and Inhibitor-Resistant TEM-30  -Lactamases in New York City

A. Bradford, Patricia; Bratu, Simona; Urban, Carl; Visalli, Maria; Mariano, N; Landman, David; J. Rahal, James; E. Brooks, Steven; Cebular, S.; Quale, John

doi:10.1086/421495

Public

Emergence of Carbapenem-Resistant Klebsiella Species Possessing the Class A Carbapenem-Hydrolyzing KPC-2 and Inhibitor-Resistant TEM-30 -Lactamases in New York City

Published in Clinical Infectious Diseases • Jun 21, 2004

Authors:

Patricia A. Bradford

Simona Bratu

Carl Urban

Abstract

Nineteen isolates of carbapenem-resistant Klebsiella species were recovered from 7 hospitals in New York City. Most K. pneumoniae belonged to a single ribotype. Nucleotide sequencing identified KPC-2, a carbapenem-hydrolyzing beta -lactamase. In 3 strains, TEM-30, an inhibitor-resistant beta -lactam...

Subject

Klebsiella pneumoniae

Microbiology

Carbapenem

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