Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine

A. Seder, Robert; Chang, Lee-Jah; E. Enama, Mary; L. Zephir, Kathryn; N. Sarwar, Uzma; J. Gordon, Ingelise; A. Holman, LaSonji; R. James, Eric; F. Billingsley, Peter; Gunasekera, Anusha; Richman, Adam; Chakravarty, Sumana; Manoj, Anita; Velmurugan, Soundarapandian; Li, MingLin; J. Ruben, Adam; Li, Tao; G. Eappen, Abraham; E. Stafford, Richard; H. Plummer, Sarah; S. Hendel, Cynthia; Novik, Laura; J. M. Costner, Pamela; H. Mendoza, Floreliz; G. Saunders, Jamie; C. Nason, Martha; H. Richardson, Jason; Murphy, Jittawadee; A. Davidson, Silas; L. Richie, Thomas; Sedegah, Martha; Sutamihardja, Awalludin; A. Fahle, Gary; E. Lyke, Kirsten; B. Laurens, Matthew; Roederer, Mario; Tewari, Kavita; E. Epstein, Judith; Kim Lee Sim, B.; E. Ledgerwood, Julie; S. Graham, Barney; L. Hoffman, Stephen; VRC 312 Study Team, the; DiGiovanni, Cassandra; Williams, Pernell; Luongo, Nicole; Mitchell, Jillian; Burgos Florez, Maria; Larkin, Brenda; Berkowitz, Nina; Wilson, Brandon; Clarke, Tanya; Vasilenko, Olga; Yamshchikov, Galina; Sitar, Sandra; Stanford, LaChonne; Pittman, Iris; T. Bailer, Robert; Casazza, Joseph; Decederfelt, Hope; Starling, Judith; C. Williams, Esther; Lau, Anna; Antonara, Stella; Brocious, Jeffery; Kemp, Margaret; Inglese, James; Dranchak, Patricia; N. Abot, Esteban; Reyes, Sharina; Ganeshan, Harini; Belmonte, Maria; Huang, Jun; Belmonte, Arnel; Komisar, Jack; Abebe, Yonas; Getachew, Yeab; Patil, Asha; Matheny, Steve; Nelson, Keith; Overby, James; Pich, Virak; Wen, Yingda; Fan, Richard; Fomumbod, Enni; Awe, Aderonke; Chakiath, Chinnamma; King, Mary; Socorro Orozco, Maria; Murshedkar, Tooba; Padilla, Debbie; Jiang, Bing; Gao, Lixin; KC, Natasha; Xu, Rui; Adams, Matthew; Plowe, Christopher; Loblein, Hayley; Zaia Renehan, Phyllis; Kunchai, Meghan; Diep, Ly

doi:10.1126/science.1241800

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Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine

Shared by NobleBlocks on Sep 20, 2013 • 12:00 AM UTC

Authors:

Robert A. Seder

Lee-Jah Chang

Mary E. Enama

Abstract

Malaria Sporozoite Vaccine Each year, hundreds of millions of people are infected with Plasmodium falciparum , the mosquito-borne parasite that causes malaria. A preventative vaccine is greatly needed. Seder et al. (p. 1359 , published online 8 August; see the Perspective by Good ) now report the re...

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