Postoperative Irradiation with or without Concomitant Chemotherapy for Locally Advanced Head and Neck Cancer

Bernier, Jacques; Domenge, C.; Özsahin, Mahmut; Łukawska‐Matuszewska, Katarzyna; Lefèbvre, Jean-Louis; Greiner, Richard; Giralt, J.; Maingon, P.; Rolland, Frédéric; Bolla, M.; Cognetti, F.; Bourhis, Jean; Kirkpatrick, Anne; van Glabbeke, M.

doi:10.1056/nejmoa032641

Public

Postoperative Irradiation with or without Concomitant Chemotherapy for Locally Advanced Head and Neck Cancer

Published in New England Journal of Medicine • May 5, 2004

Authors:

Jacques Bernier

C. Domenge

Mahmut Özsahin

Abstract

BACKGROUND: We compared concomitant cisplatin and irradiation with radiotherapy alone as adjuvant treatment for stage III or IV head and neck cancer. METHODS: After undergoing surgery with curative intent, 167 patients were randomly assigned to receive radiotherapy alone (66 Gy over a period of 6 1/...

Subject

Medicine

Concomitant

Head and neck cancer

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