Qualimap: evaluating next-generation sequencing alignment data

García-Alcalde, Fernando; Okonechnikov, Konstantin; Carbonell‐Caballero, José; Miguel González Cruz, Luis; Götz, Stefan; Tarazona, Sonia; Dopazo, Joaquı́n; F. Meyer, Thomas; Conesa, Ana

doi:10.1093/bioinformatics/bts503

Public

Qualimap: evaluating next-generation sequencing alignment data

Published in Bioinformatics • Aug 22, 2012

Authors:

Fernando García-Alcalde

Konstantin Okonechnikov

José Carbonell‐Caballero

Abstract

MOTIVATION: The sequence alignment/map (SAM) and the binary alignment/map (BAM) formats have become the standard method of representation of nucleotide sequence alignments for next-generation sequencing data. SAM/BAM files usually contain information from tens to hundreds of millions of reads. Often...

Subject

Computer science

Data mining

Sequence (biology)

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