Using the miraEST Assembler for Reliable and Automated mRNA Transcript Assembly and SNP Detection in Sequenced ESTs

Chevreux, Bastien; Pfisterer, Thomas; Drescher, Bernd; Driesel, A.J.; E.G. Müller, Wernér; C. Wetter, Thomas; Suhai, Sándor

doi:10.1101/gr.1917404

Public

Using the miraEST Assembler for Reliable and Automated mRNA Transcript Assembly and SNP Detection in Sequenced ESTs

Published in Genome Research • May 12, 2004

Authors:

Bastien Chevreux

Thomas Pfisterer

Bernd Drescher

Abstract

We present an EST sequence assembler that specializes in reconstruction of pristine mRNA transcripts, while at the same time detecting and classifying single nucleotide polymorphisms (SNPs) occuring in different variations thereof. The assembler uses iterative multipass strategies centered on high-c...

Subject

Biology

Computational biology

Sequence (biology)

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