SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing

Bankevich, Anton; Nurk, Sergey; Antipov, Dmitry; Gurevich, Alexey; Dvorkin, Mikhail; S. Kulikov, Alexander; M. Lesin, Valery; Nikolenko, Sergey; Pham, Son; D. Prjibelski, Andrey; Pyshkin, Alexey; Sirotkin, Alexander; Vyahhi, Nikolay; Tesler, Glenn; A. Alekseyev, Max; A. Pevzner, Pavel

doi:10.1089/cmb.2012.0021

Public

SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing

Published in Journal of Computational Biology • Apr 16, 2012

Authors:

Anton Bankevich

Sergey Nurk

Dmitry Antipov

Abstract

The lion's share of bacteria in various environments cannot be cloned in the laboratory and thus cannot be sequenced using existing technologies. A major goal of single-cell genomics is to complement gene-centric metagenomic data with whole-genome assemblies of uncultivated organisms. Assembly of si...

Subject

Metagenomics

Sequence assembly

Genome

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