Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease

Dichgans, Martin; Malik, Rainer; R. König, Inke; Rosand, Jonathan; Clarke, Robert; Grétarsdóttir, Sólveig; Þorleifsson, Guðmar; D. Mitchell, Braxton; L. Assimes, Themistocles; Levi, Christopher; J O Donnell, Christopher; Fornage, Myriam; Þorsteinsdóttir, Unnur; M. Psaty, Bruce; Hengstenberg, Christian; Seshadri, Sudha; Erdmann, Jeanette; C. Bis, Joshua; Peters, Annette; B. Boncoraglio, Giorgio; März, Winfried; F. Meschia, James; Kathiresan, Sekar; Arfan Ikram, M.; McPherson, Ruth; Stefánsson, Kāri; Sudlow, Cathie; P. Reilly, Muredach; Thompson, J.; Sharma, Pankaj; C. Hopewell, Jemma; C. Chambers, John; Watkins, Hugh; M. Rothwell, Peter; J. Roberts, Robert; S. Markus, Hugh; J. Samani, Nilesh; Farrall, Martin; Schunkert, Heribert; tier of authors:, Collaborators/second; Gschwendtner, Andreas; Bevan, Steve; Chen, Yu‐Ching; L. DeStefano, Anita; Parati, Eugenio; Quertermous, Tom; Ziegler, Andreas; Boerwinkle, Eric; Hólm, Hilma; Fischer, Marcus; Kessler, Thorsten; Willenborg, Christina; Laaksonen, Reijo; F. Voight, Benjamin; F.R. Stewart, Alexandre; J. Rader, Daniel; S. Hall, Alistair; S. Kooner, Jaspal

doi:10.1161/strokeaha.113.002707

Public

Shared Genetic Susceptibility to Ischemic Stroke and Coronary Artery Disease

Published in Stroke • Nov 22, 2013

Authors:

Martin Dichgans

Rainer Malik

Inke R. König

Abstract

BACKGROUND AND PURPOSE: Ischemic stroke (IS) and coronary artery disease (CAD) share several risk factors and each has a substantial heritability. We conducted a genome-wide analysis to evaluate the extent of shared genetic determination of the two diseases. METHODS: Genome-wide association data wer...

Subject

Genome-wide association study

Coronary artery disease

Medicine

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